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She referred to the Multicentre App reviews Huskvarna of In vitro Cytotoxicity MEIC project, which was the first study that showed that human cells predict human toxicity better than cells from any other species and even mice and rats Ekwall et al.

Convinced about the fact that human cells are the only relevant tissue for human safety assessment, Nkrrtalje has developed and used human cell and tissue models throughout decades. These skin-derived, differentiated hepatic progenitor cells have been shown to be useful for estimation of toxicological responses such as liver damage, liver necrosis and steatosis by using a toxicogenomic approach.

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Again, Vera Rogiers and her research team present a novel, innovative human cell model that can be used for human safety assessment. Department of Neurochemistry. Ekwall B.

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